Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223447 | 0.86 | EGFR (0.53) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL7835295 | 0.76 | KDM4E (0.46) | EGFRERBB2MEN1KMT2AKDM4E | |
| SCHEMBL4782949 | 0.75 | MEN1 (0.61) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11566550 | 0.74 | KDM4E (0.54) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL250872 | 0.72 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL19708072 | 0.72 | MEN1 (0.66) | MEN1KMT2ATSHRMAPTMAPK1 | |
| SCHEMBL2640927 | 0.71 | MEN1 (0.69) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL7837784 | 0.70 | LMNA (0.51) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL24347999 | 0.70 | PTGS2 (0.67) | EGFRERBB2MEN1KMT2AKDM4E | |
| SCHEMBL15912975 | 0.70 | HSD11B1 (0.50) | EGFRERBB2ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365990-A | Sulfonylurea herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4260824-A | Sulfonylurea herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-04-07 | — | — | US | disclosed |