Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230947 | 0.82 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL5655235 | 0.82 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL4783086 | 0.77 | MAPT (0.49) | MAPTKDM4EALDH1A1MAOBPOLB | |
| SCHEMBL5655023 | 0.75 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL1436714 | 0.72 | CYP1A2 (0.36) | — | |
| SCHEMBL14587873 | 0.71 | MAPT (0.36) | MAPTALDH1A1POLB | |
| SCHEMBL8921624 | 0.70 | MEN1 (0.40) | MAPTALDH1A1 | |
| SCHEMBL5239685 | 0.69 | PABPC1 (0.32) | MAPTPOLB | |
| Hydrochloric Acid SCHEMBL10338723 | 0.69 | MEN1 (0.39) | MAPTALDH1A1 | |
| Sulfuric Acid SCHEMBL5278578 | 0.67 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047210-A2 | COMPOUNDS DERIVED FROM 1 -ETHYL-4,5-DIAMINO-PYRAZOLE AND THEIR USE FOR OXIDATIVE DYEING OF KERATIN FIBRES | KEMON S.P.A. (IT) | 2008-04-24 | — | — | WO | disclosed |