Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655235 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAASMN1; SMN2USP2 | |
| SCHEMBL4783087 | 0.82 | MAPT (0.48) | ALDH1A1KDM4EMAPTGRIN2DGRIN3B | |
| SCHEMBL5228305 | 0.80 | NPC1 (0.46) | ALDH1A1KDM4EGAASMN1; SMN2USP2 | |
| SCHEMBL5228289 | 0.80 | NPC1 (0.46) | ALDH1A1KDM4EGAASMN1; SMN2USP2 | |
| SCHEMBL5655023 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL5655026 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL14587873 | 0.78 | MAPT (0.36) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL1436714 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL14587874 | 0.73 | GAA (0.46) | ALDH1A1KDM4EGAAUSP2MEN1 | |
| Hydrochloric Acid SCHEMBL5277328 | 0.72 | CYP1A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | KRT18, NOX5, TUBB3 | ALDH1A1 193/4885KDM4E 1607/4885GAA 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.