Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | CTSG | P08311 | 5/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.34 |
| ▸ | CMA1 | P23946 | 5/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783192 | 1.00 | TDP1 (0.41) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL4733828 | 0.82 | TSHR (0.61) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL4733821 | 0.82 | TSHR (0.61) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL28733 | 0.80 | TDP1 (0.64) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL28732 | 0.75 | TDP1 (0.56) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL4732195 | 0.74 | LMNA (0.42) | TDP1ALDH1A1TSHRLMNACES2 | |
| SCHEMBL4732201 | 0.74 | LMNA (0.42) | TDP1ALDH1A1TSHRLMNACES2 | |
| SCHEMBL7907952 | 0.73 | ALDH1A1 (0.46) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL43962 | 0.73 | TDP1 (0.72) | TDP1ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL5001492 | 0.72 | LMNA (0.30) | HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250739-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-10-16 | — | — | US | disclosed |
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| EP-0785964-B1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | DOW CHEMICAL CO (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5830924-A | LOW DENSITY CLOSED CELL, BLOWING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0785957-B1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | DOW CHEMICAL CO (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0785957-A1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011962-A1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |