Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732195 | 1.00 | LMNA (0.42) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL4733264 | 0.86 | SMN1; SMN2 (0.41) | LMNATDP1HPGDRAB9ANR1H4 | |
| SCHEMBL4733257 | 0.86 | SMN1; SMN2 (0.41) | LMNATDP1HPGDRAB9ANR1H4 | |
| SCHEMBL27904265 | 0.80 | CES2 (0.53) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL98564 | 0.79 | LMNA (0.58) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL2515769 | 0.78 | LMNA (0.56) | LMNACES2CES1TSHRL3MBTL1 | |
| Benzoyl Peroxide SCHEMBL10537673 | 0.78 | LMNA (0.59) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL28161778 | 0.76 | LMNA (0.54) | LMNACES2CES1TSHRL3MBTL1 | |
| Benzoic Acid SCHEMBL1411636 | 0.75 | TSHR (0.59) | LMNACES2CES1TSHRL3MBTL1 | |
| Benzoic Acid SCHEMBL9668494 | 0.75 | LMNA (0.53) | LMNATSHRL3MBTL1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | claimed |