Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | UBE2M | P61081 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737156 | 0.87 | FASN (0.72) | FASNMEN1KMT2APRSS12TP53 | |
| SCHEMBL4737584 | 0.85 | FASN (0.74) | FASN | |
| SCHEMBL4735742 | 0.85 | FASN (0.64) | FASNUBE2MDCUN1D1 | |
| SCHEMBL4735653 | 0.85 | HSD11B1 (0.60) | FASNMEN1KMT2APRSS12ALDH1A1 | |
| SCHEMBL4736922 | 0.84 | FASN (0.71) | FASN | |
| SCHEMBL4183548 | 0.84 | L3MBTL1 (0.54) | FASNMEN1KMT2APRSS12ALDH1A1 | |
| SCHEMBL4738327 | 0.84 | FASN (0.52) | FASNPRSS12CCR1UBE2MDCUN1D1 | |
| SCHEMBL16799151 | 0.83 | FASN (0.56) | FASNPRSS12 | |
| SCHEMBL4735774 | 0.83 | FASN (0.64) | FASN | |
| SCHEMBL4737762 | 0.82 | HSD11B1 (0.57) | FASNMEN1KMT2APRSS12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | claimed |
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |