Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL478325 | 1.00 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL8845344 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29775 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9405236 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL66313 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9134521 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28145127 | 0.95 | CA4 (0.85) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1065771 | 0.94 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1741351 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL2460192 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3457848-B1 | AGROCHEMICAL COMBINATION | CROP INTELLECT LTD (GB) | 2024-08-07 | — | — | EP | claimed |
| US-10912295-B2 | Agrochemical combination | CROP INTELLECT LTD. (GB) | 2021-02-09 | — | — | US | claimed |
| EP-3457848-B1 | AGROCHEMICAL COMBINATION | CROP INTELLECT LTD (GB) | 2024-08-07 | — | — | EP | disclosed |
| US-11134620-B2 | Use of bentonite for improving plant growth-related traits | SCANNELL CHRISTOPHER (US) | 2021-10-05 | — | — | US | disclosed |
| US-10912295-B2 | Agrochemical combination | CROP INTELLECT LTD. (GB) | 2021-02-09 | — | — | US | disclosed |
| US-10793481-B2 | Methods for treating a plant exposed to a phytotoxicant | YAMASHITA THOMAS T (US) | 2020-10-06 | — | — | US | disclosed |
| US-10683244-B2 | Method for controlling plant parasitic nematodes | YAMASHITA THOMAS T (US) | 2020-06-16 | — | — | US | disclosed |
| US-10683238-B2 | Fertilizer compositions comprising a cellulose nutrient component and methods for using same | YAMASHITA THOMAS T (US) | 2020-06-16 | — | — | US | disclosed |
| US-10638785-B2 | Liquid dietary supplement formulation compositions | Watermins, LLC (US) | 2020-05-05 | — | — | US | disclosed |
| US-10570067-B2 | Compositions for enhancing pollination and methods for using same | YAMASHITA THOMAS T (US) | 2020-02-25 | — | — | US | disclosed |
| US-20200037614-A1 | USE OF BENTONITE FOR IMPROVING PLANT GROWTH-RELATED TRAITS | SCANNELL CHRISTOPHER (US) | 2020-02-06 | — | — | US | disclosed |
| EP-0544759-A1 | DETOXIFICATION OF SOIL. | YAMASHITA THOMAS T (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0514451-A1 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS. | UNIV TEXAS (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1992003393-A1 | DETOXIFICATION OF SOIL | YAMASHITA THOMAS T (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0433394-A4 | METHOD OF APPLYING ENERGY, CARBON SKELETON AND NUTRIENT MATERIALSTO VEGETATION | — | 1991-09-25 | — | — | EP | disclosed |
| WO-1991013844-A1 | METHOD AND COMPOSITION FOR PROMOTING AND CONTROLLING GROWTH OF PLANTS | YAMASHITA THOMAS T (US) | 1991-09-19 | — | — | WO | disclosed |
| WO-1991011117-A2 | DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-08-08 | — | — | WO | disclosed |
| EP-0433394-A1 | METHOD OF APPLYING ENERGY, CARBON SKELETON AND NUTRIENT MATERIALSTO VEGETATION. | YAMASHITA THOMAS T (US) | 1991-06-26 | — | — | EP | disclosed |
| WO-1990002719-A1 | METHOD OF APPLYING ENERGY, CARBON SKELETON AND NUTRIENT MATERIALSTO VEGETATION | YAMASHITA THOMAS T (US) | 1990-03-22 | — | — | WO | disclosed |
| US-4206233-A | Microbiocidal quaternaries of halogen derivatives of alkynoxymethyl amines | PETROLITE CORPORATION (US) | 1980-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10912295-B2 | Agrochemical combination | PLD1, ITPA, PLD2 | CA4 3185/4885ALDH1A1 705/4885CASP1 3125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.