Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580567 | 0.78 | PRKCQ (0.41) | KMT2APRKCQMAPTPRKCDCXCR6 | |
| SCHEMBL4581544 | 0.78 | PRKCQ (0.42) | PRKCQMAPTPRKCDCXCR6 | |
| SCHEMBL4581014 | 0.77 | PRKCQ (0.40) | KMT2APRKCQMAPTPRKCDCXCR6 | |
| SCHEMBL4581125 | 0.76 | SRC (0.41) | KMT2APRKCQPRKCDCXCR6MEN1 | |
| SCHEMBL4580274 | 0.76 | PRKCQ (0.38) | SMN1; SMN2KMT2APRKCQNPC1RAB9A | |
| SCHEMBL4580030 | 0.76 | PRKCQ (0.38) | KMT2APRKCQNPC1RAB9AMAPT | |
| SCHEMBL4783392 | 0.75 | PRKCQ (0.39) | PRKCQNPC1RAB9AMAPTPRKCD | |
| SCHEMBL4582342 | 0.73 | TUBB4A (0.41) | SMN1; SMN2KMT2ACXCR6TUBB4ATUBB | |
| SCHEMBL4581296 | 0.71 | TBK1 (0.42) | SMN1; SMN2KMT2APRKCQMAPTPRKCD | |
| SCHEMBL4579980 | 0.71 | KDM4E (0.48) | SMN1; SMN2CYP1A2CYP2C9MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024963-A1 | BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | disclosed |