Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 7/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581544 | 0.81 | PRKCQ (0.42) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4579980 | 0.76 | KDM4E (0.48) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4580694 | 0.75 | MAPT (0.44) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4581755 | 0.75 | ALDH1A1 (0.42) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4783383 | 0.75 | SMN1; SMN2 (0.45) | PRKCQPRKCDMAPTCXCR6NPC1 | |
| SCHEMBL4580030 | 0.74 | PRKCQ (0.38) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4581125 | 0.73 | SRC (0.41) | PRKCQPRKCDALDH1A1CXCR6 | |
| SCHEMBL4580274 | 0.72 | PRKCQ (0.38) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4579724 | 0.71 | PGR (0.50) | PRKCQPRKCDKDM4EALDH1A1GAA | |
| SCHEMBL4580567 | 0.71 | PRKCQ (0.41) | PRKCQPRKCDKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024963-A1 | BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | disclosed |