Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DDT | P30046 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779406 | 0.87 | RXFP1 (0.42) | RXFP1MAPTNAMPTEGLN1ALDH1A1 | |
| SCHEMBL4782951 | 0.86 | BRAF (0.37) | — | |
| SCHEMBL4779417 | 0.83 | MAPK14 (0.49) | RXFP1MAPTNAMPTMAPK14DHODH | |
| SCHEMBL4780823 | 0.82 | ACKR3 (0.39) | ALDH1A1DHODH | |
| SCHEMBL4781720 | 0.77 | MAPK14 (0.43) | MAPTALDH1A1NPSR1MAPK14DHODH | |
| SCHEMBL4782954 | 0.77 | BRAF (0.40) | — | |
| SCHEMBL4730134 | 0.74 | RAF1 (0.49) | MAPTMAPK14 | |
| SCHEMBL4780831 | 0.73 | TNK2 (0.39) | ALDH1A1DHODH | |
| SCHEMBL4778219 | 0.71 | NAPEPLD (0.40) | MAPK14 | |
| SCHEMBL4781726 | 0.71 | MAPK14 (0.41) | MAPTALDH1A1NPSR1MAPK14DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |