Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501378 | 0.92 | MRGPRX4 (0.41) | PRKCIKDR | |
| SCHEMBL4727676 | 0.85 | CYP4F2 (0.44) | PRKCIAGXTF2 | |
| SCHEMBL3426549 | 0.82 | AGXT (0.41) | AGXTF2 | |
| SCHEMBL1206636 | 0.81 | CA12 (0.38) | KDRF2 | |
| SCHEMBL840465 | 0.81 | GABRA1 (0.45) | — | |
| SCHEMBL22262854 | 0.81 | IRAK4 (0.44) | PRKCIKDRCDK8S1PR1S1PR3 | |
| SCHEMBL5871245 | 0.80 | CYP4F2 (0.43) | AGXTACMSDCDK8 | |
| SCHEMBL7174917 | 0.80 | CA2 (0.37) | F2 | |
| SCHEMBL15125782 | 0.79 | PRKCI (0.50) | PRKCIFGFR1ACMSDCHRNB4CHRNA3 | |
| SCHEMBL3432959 | 0.79 | AGXT (0.38) | AGXTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033455-A2 | BIPHENYL AND HETEROARYL PHENYL DERIVATIVES AS PROTEIN TYROSINE PHOSPHATASES INHIBITORS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-03-20 | — | — | WO | disclosed |