Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738064 | 0.92 | AVPR1A (0.34) | CNR1ALDH1A1MEN1KMT2AAVPR1A | |
| SCHEMBL4740444 | 0.87 | HCAR2 (0.34) | ALDH1A1TP53 | |
| SCHEMBL4734328 | 0.86 | CCNC (0.32) | ALDH1A1TP53 | |
| SCHEMBL4784972 | 0.84 | NPY5R (0.33) | ALDH1A1TP53 | |
| SCHEMBL4735029 | 0.84 | NPY5R (0.33) | ALDH1A1KDM4ETP53 | |
| SCHEMBL4737642 | 0.83 | NPY5R (0.37) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL4735036 | 0.82 | CNR1 (0.36) | CNR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4739249 | 0.81 | PIN1 (0.31) | — | |
| SCHEMBL4737057 | 0.81 | OPRL1 (0.36) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL4734384 | 0.81 | KMT2A (0.36) | CNR1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | claimed |