SCHEMBL4783808

SCHEMBL4783808

CC(=O)C(O)(C[N+](C)(C)C)C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ACHE P22303 1/20 0.33
CHRM1 P11229 3/20 0.32
CHRM5 P08912 2/20 0.32
CHRM3 P20309 2/20 0.32
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
TBXA2R P21731 2/20 0.32
PGR P06401 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRNA10 Q9GZZ6 1/20 0.32
CHRNA9 Q9UGM1 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10633358 0.97 ALDH1A1 (0.36) TSHRACHECHRM1CHRM5CHRM3
SCHEMBL4550498 0.70 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL29497518 0.67 CA4 (0.46) ALDH1A1
SCHEMBL30160923 0.67 CA4 (0.46) ALDH1A1
SCHEMBL8524045 0.67 ALDH1A1 (0.39) TSHRCHRM1TBXA2RALDH1A1LMNA
SCHEMBL1925937 0.67 ALDH1A1 (0.32) TSHRCHRM1TBXA2RALDH1A1LMNA
Hydrochloric Acid SCHEMBL31574660 0.66 CA4 (0.45)
SCHEMBL7158911 0.65
SCHEMBL27633145 0.65 GAA (0.41) TSHRCHRM1CHRM5CHRM3CHRM2
SCHEMBL2142716 0.65 KDM4E (0.35) ALDH1A1LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622913-B2 Folate salts for medical use APROFOL AG (CH) 2026-05-12 US claimed
US-20230277544-A1 FOLATE SALTS FOR MEDICAL USE APROFOL AG (CH) 2023-09-07 US claimed
US-20200261460-A1 FOLATE SALTS FOR MEDICAL USE APROFOL AG (CH) 2020-08-20 US claimed
EP-3687995-A1 FOLATE SALTS FOR MEDICAL USE Aprofol AG (CH) 2020-08-05 EP claimed
CN-111448196-A Folates for medical use 阿普罗福尔公司 2020-07-24 CN claimed
WO-2019063236-A1 FOLATE SALTS FOR MEDICAL USE APROFOL AG (CH) 2019-04-04 WO claimed
EP-3461826-A1 MULTIFUNCTIONAL FOLATE SALTS Aprofol AG (CH) 2019-04-03 EP claimed
US-12622913-B2 Folate salts for medical use APROFOL AG (CH) 2026-05-12 US disclosed
CN-118126843-A Monascus strain and application thereof in preparation of fermented tea 安徽德昌药业股份有限公司 2024-06-04 CN disclosed
US-20230277544-A1 FOLATE SALTS FOR MEDICAL USE APROFOL AG (CH) 2023-09-07 US disclosed
US-11690846-B2 Folate salts for medical use APROFOL AG 2023-07-04 US disclosed
CN-107108837-B Thermoplastic polyurethane films for delivering active agents to skin surfaces 路博润先进材料公司 2021-04-13 CN disclosed
US-20200261460-A1 FOLATE SALTS FOR MEDICAL USE APROFOL AG (CH) 2020-08-20 US disclosed
WO-2019063236-A1 FOLATE SALTS FOR MEDICAL USE APROFOL AG (CH) 2019-04-04 WO disclosed
EP-3461826-A1 MULTIFUNCTIONAL FOLATE SALTS Aprofol AG (CH) 2019-04-03 EP disclosed
WO-2008021552-A9 BIASED LIGANDS AND METHODS OF IDENTIFYING SAME UNIV DUKE (US) 2008-05-29 WO disclosed
WO-2008021552-A2 BIASED LIGANDS AND METHODS OF IDENTIFYING SAME DUKE UNIVERSITY (US) 2008-02-21 WO disclosed
US-6303588-B1 APPLYING TO PORTIONS OF THE SKIN OF SUCH PATIENT WHICH HAVE ABNORMAL SKIN CELL METABOLISM BIOACTIVE AGENT COMPRISING ADENOSINE-5-TRIPHOSPHATE, QUANOSINE-5-TRIPHOSPHATE AND PHOSPHINOSITEDES AND BIOLOGICALLY ACCEPTABLE CARRIER Danielov, Michael M. 2001-10-16 US disclosed
US-5885974-A DECREASES THE DOSAGE OF BIOACTIVE AGENT NECESSARY, WHEN ADMINISTERED TO A PATIENT WITH ABNORMAL CELL METABOLISM, TO CORRECT THE ABNORMAL CELL METABOLISM AND PROMOTE THE RESUMPTION OF NORMAL CELL METABOLISM Danielov, Michael M. (US) 1999-03-23 US disclosed
WO-1996017621-A1 CORRECTING BIOLOGICAL INFORMATION TRANSFER USING THREE BIOLOGICAL INFORMATION BLOCKS DNS SCIENTIFIC, INC. (US) 1996-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261460-A1 FOLATE SALTS FOR MEDICAL USE FOLR2, FOLR1, MTHFD1 TSHR 4388/4885ACHE 1267/4885CHRM1 102/4885
US-11690846-B2 Folate salts for medical use FOLR2, FOLR1, MTHFD1 TSHR 4388/4885ACHE 1267/4885CHRM1 102/4885
US-20230277544-A1 FOLATE SALTS FOR MEDICAL USE FOLR2, FOLR1, MTHFD1 TSHR 4635/4885ACHE 1042/4885CHRM1 92/4885
US-12622913-B2 Folate salts for medical use FOLR2, FOLR1, MTHFD1 TSHR 4099/4885ACHE 1158/4885CHRM1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.