Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146845 | 0.85 | HRH4 (0.53) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4738132 | 0.85 | HPGD (0.52) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4783417 | 0.84 | HPGD (0.51) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14146842 | 0.82 | AKR1C3 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL1458624 | 0.75 | L3MBTL1 (0.73) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL28494646 | 0.75 | MEN1 (0.67) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL15004819 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL5233751 | 0.71 | L3MBTL1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL14147625 | 0.70 | KMT2A (0.54) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4784271 | 0.70 | KMT2A (0.57) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |