Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100919 | 0.99 | AGTR2 (0.84) | AGTR2AGTR1 | |
| SCHEMBL9134474 | 0.95 | AGTR2 (0.84) | AGTR2AGTR1 | |
| Potassium Ion SCHEMBL30604717 | 0.93 | AGTR2 (0.84) | AGTR2AGTR1 | |
| Potassium Ion SCHEMBL612505 | 0.93 | AGTR2 (0.84) | AGTR2AGTR1 | |
| SCHEMBL8976768 | 0.92 | AGTR2 (0.98) | AGTR2AGTR1 | |
| SCHEMBL8976602 | 0.91 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL7701057 | 0.91 | AGTR2 (1.00) | AGTR2AGTR1 | |
| Potassium SCHEMBL8976441 | 0.90 | AGTR2 (0.98) | AGTR2AGTR1 | |
| SCHEMBL7021272 | 0.86 | AGTR2 (1.00) | AGTR2AGTR1 | |
| SCHEMBL9134993 | 0.85 | AGTR2 (0.84) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283480-A1 | AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS | BAUSCH HEALTH COMPANIES INC. (CA) | 2020-09-10 | — | — | US | disclosed |
| WO-2008039829-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| EP-1851197-A2 | PHENYLAZETIDINONE DERIVATIVES | Microbia, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006086562-A2 | PHENYLAZETIDINONE DERIVATIVES | MICROBIA, INC. (US) | 2006-08-17 | — | — | WO | disclosed |