Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140705 | 0.75 | MEN1 (0.47) | PTPN1PTPRCPARK7ALDH1A1CASP3 | |
| Phosphine SCHEMBL14764881 | 0.74 | MEN1 (0.46) | PTPN1PTPRCPARK7ALDH1A1CASP3 | |
| SCHEMBL4848431 | 0.70 | PTPN1 (0.69) | PTPN1PARK7ALDH1A1CNR1PPARG | |
| SCHEMBL3807551 | 0.70 | STAT3 (0.33) | TOP2A | |
| SCHEMBL2860815 | 0.70 | GABRA1 (0.39) | PTPRCTOP2AALDH1A1CASP3GABRA1 | |
| SCHEMBL9791396 | 0.68 | MEN1 (0.36) | TOP2AALDH1A1GABRA1GABRB2KMT2A | |
| SCHEMBL11218822 | 0.68 | MAPT (0.54) | TOP2AALDH1A1GABRA1GABRB2KMT2A | |
| SCHEMBL15732904 | 0.66 | SOAT1 (0.43) | PTPN1ALDH1A1KMT2ANSD2LMNA | |
| SCHEMBL4785447 | 0.63 | MAPT (0.40) | TOP2AALDH1A1CASP3GABRA1GABRB2 | |
| SCHEMBL10747842 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008136642-A1 | NAPHTHOQUINONE-BASED PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | MAZENCE INC. (KR) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008066300-A1 | NAPHTHOQUINONE-BASED PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | MAZENCE INC. (KR) | 2008-06-05 | — | — | WO | disclosed |