Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784358 | 0.91 | TBXAS1 (0.48) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL4782630 | 0.89 | KMT2A (0.48) | MEN1KMT2ATDP1GAAALDH1A1 | |
| SCHEMBL4784291 | 0.85 | TDP1 (0.54) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL4784579 | 0.83 | TDP1 (0.54) | MEN1KMT2ATDP1GAAALDH1A1 | |
| SCHEMBL4782569 | 0.83 | TDP1 (0.51) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL4783597 | 0.81 | TDP1 (0.51) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL4785325 | 0.81 | TDP1 (0.51) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL4785858 | 0.78 | MEN1 (0.62) | MEN1KMT2ALMNASMN1; SMN2HTR6 | |
| SCHEMBL4782509 | 0.77 | MEN1 (0.61) | MEN1KMT2ALMNASMN1; SMN2HTR6 | |
| SCHEMBL4781216 | 0.76 | TBXAS1 (0.47) | TDP1SMN1; SMN2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |