Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884290 | 0.70 | MYC (0.46) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL28542992 | 0.70 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL6208037 | 0.68 | DYRK1A (0.52) | KDM4EHPGDTSHRKDM3BDYRK1A | |
| SCHEMBL30159879 | 0.67 | ALDH1A1 (0.58) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL6105725 | 0.67 | ALDH1A1 (0.58) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL3539779 | 0.67 | SMN1; SMN2 (0.38) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL6207480 | 0.66 | KDM4E (0.44) | KDM4EALDH1A1HPGDHTTKDM3B | |
| SCHEMBL27844750 | 0.66 | POLB (0.43) | MAPTALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL27919854 | 0.65 | IP6K1 (0.57) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL5532623 | 0.65 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070350-A9 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | UNIV TEXAS (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008070350-A2 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-06-12 | — | — | WO | disclosed |