Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208722 | 0.86 | KDM4E (0.44) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6207870 | 0.78 | KDM4E (0.41) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6207236 | 0.77 | DYRK1A (0.47) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6208699 | 0.77 | KDM4E (0.43) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL27695803 | 0.76 | HCAR2 (0.43) | KDM4EKDM3BCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL6206909 | 0.75 | KDM4E (0.41) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6208037 | 0.74 | DYRK1A (0.52) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL23674962 | 0.73 | NAPRT (0.48) | KDM4EKDM3BDYRK1AGABRA1GABRB2 | |
| SCHEMBL7121722 | 0.72 | PRNP (0.38) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL10901788 | 0.71 | GABRP (0.43) | KDM4ECSNK2A1GABRA1GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546133-A2 | N-SUBSTITUTE-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031175-A2 | N-SUBSTITUTED-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | WO | disclosed |