Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 15/20 | 0.42 |
| ▸ | MTOR | P42345 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782543 | 0.94 | DGAT2 (0.42) | LMNAALDH1A1 | |
| SCHEMBL4785892 | 0.91 | PIK3CA (0.47) | PIK3CAMTORLMNAPIK3R1PIK3CB | |
| SCHEMBL4786826 | 0.88 | KDM4E (0.43) | PIK3CAPIK3CBPIK3CGPIK3CDALDH1A1 | |
| SCHEMBL4782727 | 0.84 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4785240 | 0.84 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4784742 | 0.84 | PIK3CA (0.42) | PIK3CAMTORLMNAGAAPIK3R1 | |
| SCHEMBL4785820 | 0.82 | PIK3CA (0.40) | PIK3CAMTORPIK3CBPIK3CG | |
| SCHEMBL4786376 | 0.81 | KDM4E (0.45) | PIK3CALMNAGAAALDH1A1 | |
| SCHEMBL4783022 | 0.81 | PIK3CA (0.49) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4782401 | 0.80 | PIK3CA (0.39) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |