Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.47 |
| ▸ | MTOR | P42345 | 4/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784749 | 0.91 | PIK3CA (0.42) | PIK3CAMTORPIK3R1ALDH1A1LMNA | |
| SCHEMBL4785240 | 0.89 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL4782727 | 0.89 | PIK3CA (0.58) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL4783022 | 0.87 | PIK3CA (0.49) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4884098 | 0.85 | PIK3CA (0.45) | PIK3CAMTORPIK3R1PIK3CBPIK3CD | |
| SCHEMBL4786376 | 0.84 | KDM4E (0.45) | PIK3CAKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4782543 | 0.84 | DGAT2 (0.42) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL4784166 | 0.84 | PIK3CA (0.43) | PIK3CAMTORPIK3R1PIK3CG | |
| SCHEMBL4786254 | 0.83 | PIK3CA (0.47) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4785891 | 0.83 | PIK3CA (0.46) | PIK3CAMTORPIK3R1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |