Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784933 | 0.80 | CA12 (0.38) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4786164 | 0.71 | CA2 (0.39) | CA1CA2CA12ALDH1A1LMNA | |
| SCHEMBL9958040 | 0.65 | STS (0.57) | CA2CA12STSALDH1A1SMN1; SMN2 | |
| SCHEMBL8198838 | 0.65 | CA12 (0.59) | CA1CA2CA12CA7CA14 | |
| SCHEMBL25081087 | 0.64 | ADAMTS4 (0.43) | SMN1; SMN2LMNA | |
| SCHEMBL25080792 | 0.64 | CA12 (0.57) | CA1CA2CA12CA7ALDH1A1 | |
| SCHEMBL25080867 | 0.64 | CYP4F2 (0.50) | CA1CA2CA12CA7 | |
| SCHEMBL20054187 | 0.63 | AKT1 (0.30) | — | |
| SCHEMBL2202915 | 0.63 | NPC1 (0.47) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4378238 | 0.63 | SMN1; SMN2 (0.50) | ALDH1A1TSHRALOX15SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |