Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602693 | 0.83 | S1PR1 (0.43) | KMT2AS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL4780628 | 0.83 | S1PR1 (0.43) | KMT2AS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL7501298 | 0.78 | S1PR1 (0.43) | KMT2AS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL4732559 | 0.78 | POLB (0.42) | KMT2AS1PR1S1PR3S1PR5MAPT | |
| SCHEMBL7692006 | 0.78 | S1PR1 (0.50) | KMT2AS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL13163105 | 0.75 | L3MBTL1 (0.50) | KMT2AHTTDPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL28131709 | 0.73 | S1PR1 (0.49) | KMT2AS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL3425018 | 0.73 | S1PR1 (0.44) | KMT2AS1PR1S1PR3S1PR5CYP1A2 | |
| SCHEMBL8555789 | 0.73 | CHRNB2 (0.45) | S1PR1S1PR3S1PR5CYP1A2CHRNB2 | |
| SCHEMBL7733041 | 0.72 | L3MBTL1 (0.43) | KMT2AS1PR1S1PR3S1PR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |