Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784326 | 0.91 | IDH1 (0.35) | MAPK1PDE4BPDE4DTP53PIK3CA | |
| SCHEMBL4785161 | 0.83 | CSNK1E (0.36) | PDE4BPDE4DCSNK1EJAK2BRD4 | |
| SCHEMBL4784052 | 0.78 | PIK3CA (0.38) | MAPK1BRD4TP53PIK3CA | |
| SCHEMBL4783578 | 0.77 | CSNK1E (0.43) | PDE4BPDE4DCSNK1EJAK2BRD4 | |
| SCHEMBL4784447 | 0.74 | IDH1 (0.37) | PDE4BPDE4DCSNK1ETP53 | |
| SCHEMBL4782612 | 0.73 | IDH1 (0.41) | PIK3CA | |
| SCHEMBL4782980 | 0.71 | PIK3CA (0.44) | CSNK1DPIK3CA | |
| SCHEMBL4855287 | 0.71 | PIK3CA (0.44) | PIK3CA | |
| SCHEMBL4784144 | 0.70 | IDH1 (0.42) | MAPK1PIK3CA | |
| SCHEMBL4781393 | 0.70 | PIK3CA (0.41) | PIK3CADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |