Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 6/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784447 | 0.91 | IDH1 (0.37) | CSNK1EPDE4BPDE4D | |
| SCHEMBL4785822 | 0.87 | CTSL (0.40) | PDE4BPDE4DPIK3CB | |
| SCHEMBL4857757 | 0.85 | DRD2 (0.44) | DRD2DRD4 | |
| SCHEMBL4785158 | 0.83 | MAPK1 (0.35) | CSNK1ECSNK1DPDE4BPDE4DJAK2 | |
| SCHEMBL4783578 | 0.78 | CSNK1E (0.43) | CSNK1ECSNK1DPDE4BPDE4DJAK2 | |
| SCHEMBL4784054 | 0.77 | PIK3CA (0.37) | BRD4PIK3CA | |
| SCHEMBL4784674 | 0.75 | HRH4 (0.43) | — | |
| SCHEMBL4784326 | 0.74 | IDH1 (0.35) | PDE4BPDE4DPIK3CA | |
| SCHEMBL4782447 | 0.73 | HRH4 (0.36) | PDE4BPDE4DDRD2DRD4RXFP1 | |
| SCHEMBL4785292 | 0.72 | ROCK1 (0.35) | PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |