Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683382 | 0.90 | KDR (0.51) | KDREPHX2EPHX1MEN1KMT2A | |
| SCHEMBL4784488 | 0.88 | EPHX2 (0.48) | KDREPHX2MEN1KMT2AATM | |
| SCHEMBL4687617 | 0.86 | EPHX2 (0.47) | KDREPHX2MEN1KMT2AATM | |
| SCHEMBL4787374 | 0.85 | KDR (0.54) | KDREPHX2EPHX1MEN1KMT2A | |
| SCHEMBL4787176 | 0.84 | TBXA2R (0.57) | EPHX2MEN1KMT2ATBXA2RMAPT | |
| SCHEMBL4233572 | 0.83 | TAS1R3 (0.55) | KDRMEN1KMT2APDGFRAKDM4E | |
| SCHEMBL4788372 | 0.80 | LMNA (0.44) | KDREPHX2MEN1KMT2AATM | |
| SCHEMBL4787232 | 0.80 | EPHX2 (0.48) | KDREPHX2EPHX1MEN1KMT2A | |
| SCHEMBL4787261 | 0.79 | KDR (0.52) | KDREPHX2EPHX1MEN1KMT2A | |
| SCHEMBL4787266 | 0.78 | EPHX2 (0.51) | EPHX2EPHX1TBXA2RMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |