Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.63 |
| ▸ | HTR3B | O95264 | 4/20 | 0.63 |
| ▸ | HTR3A | P46098 | 4/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621986 | 0.79 | MAPT (0.41) | TSHRMAPTSLC6A4KCNH2 | |
| SCHEMBL7281727 | 0.79 | KCNH2 (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7652481 | 0.79 | HTR3A (0.75) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7652475 | 0.79 | HTR3A (0.75) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL1103723 | 0.78 | HTR3E (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL30954638 | 0.78 | HTR3E (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL221830 | 0.78 | HTR3E (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Benzoyl Tropine SCHEMBL3498565 | 0.77 | HTR3E (0.97) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6506216 | 0.74 | HTR3A (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5789144 | 0.74 | HTR3A (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098329-A2 | PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL PRODUCT, OBTAINING PROCESSES OF PHARMACEUTICAL COMPOUNDS AND USE OF SUCH COMPOUNDS FOR TREATING ERECTILE DYSFUNCTION | ACHÉ LABORATÓRIOS FARMACÊUTICOS S/A (BR) | 2008-08-21 | — | — | WO | disclosed |