SCHEMBL4785327

SCHEMBL4785327

C=C(C)C1CC=C(COC(=O)c2cc(O)c(O)c(O)c2)CC1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP1B1 Q16678 1/20 0.50
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.47
CES2 O00748 1/20 0.44
LMNA P02545 2/20 0.43
SERPINE1 P05121 3/20 0.42
KDM4E B2RXH2 1/20 0.41
RAB9A P51151 1/20 0.41
TRPV1 Q8NER1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676708 0.83 ALOX15 (0.47) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL674285 0.82 ALDH1A1 (0.46) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL674777 0.82 ALDH1A1 (0.46) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL674176 0.81 ALOX15 (0.50) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL1302136 0.81 ALOX15 (0.62) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL16002382 0.81 ALOX15 (0.62) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL678301 0.80 ALDH1A1 (0.49) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL12324194 0.79 ALDH1A1 (0.45) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL19919386 0.78 ALOX15 (0.62) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL16774726 0.78 ALOX15 (0.59) ALOX15ALDH1A1CYP1B1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008065527-A2 GALLIC ACID ESTERS OF FRAGRANT ALCOHOLS GHISALBERTI CARLO (BR) 2008-06-05 WO disclosed