SCHEMBL676708

SCHEMBL676708

C=C(C)[C@@H]1CC=C(COC(=O)c2cc(OC)c(OC)c(OC)c2)CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.47
CYP1B1 Q16678 1/20 0.47
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
SLC29A1 Q99808 4/20 0.44
TRPV1 Q8NER1 1/20 0.42
HTT P42858 1/20 0.42
CES2 O00748 1/20 0.42
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19101368 0.91 ALOX15 (0.41) ALOX15CYP1B1ALDH1A1SMN1; SMN2TSHR
SCHEMBL4785327 0.83 ALOX15 (0.50) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL16002382 0.78 ALOX15 (0.62) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL1302136 0.78 ALOX15 (0.62) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL12324194 0.76 ALDH1A1 (0.45) ALOX15CYP1B1ALDH1A1SMN1; SMN2TSHR
SCHEMBL16774726 0.76 ALOX15 (0.59) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL10081724 0.76 ALOX15 (0.59) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL207377 0.76 ALOX15 (0.59) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL19919386 0.76 ALOX15 (0.62) ALOX15CYP1B1ALDH1A1TSHRMAPK1
SCHEMBL17522709 0.76 ALOX15 (0.59) ALOX15CYP1B1ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239730-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-07-18 US disclosed
US-20240239730-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-07-18 US disclosed
US-20240239730-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-07-18 US disclosed
US-20230405125-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL Neonc Technologies, Inc. 2023-12-21 US disclosed
US-20210130271-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES NIH - DEITR 2021-05-06 US disclosed
US-20210130271-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES NIH - DEITR 2021-05-06 US disclosed
EP-3769754-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES Neonc Technologies, Inc. (US) 2021-01-27 EP disclosed
US-10899691-B2 Pharmaceutical compositions comprising monoterpenes Neonc Technologies, Inc. (US) 2021-01-26 US disclosed
EP-2542082-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING (S)-perillyl alcohol NEONC TECH INC (US) 2020-05-06 EP disclosed
EP-2542082-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING (S)-perillyl alcohol NEONC TECH INC (US) 2020-05-06 EP disclosed
US-9133085-B2 Pharmaceutical compositions comprising monoterpenes NEONC TECHNOLOGIES INC (US) 2015-09-15 US disclosed
US-20130303807-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES UNIVERSITY OF SOUTHERN CALIFORNIA 2013-11-14 US disclosed
US-20130303807-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES UNIVERSITY OF SOUTHERN CALIFORNIA 2013-11-14 US disclosed
US-20130303807-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES UNIVERSITY OF SOUTHERN CALIFORNIA 2013-11-14 US disclosed
US-8507734-B2 Pharmaceutical compositions comprising monoterpenes NEONC TECHNOLOGIES INC. (US) 2013-08-13 US disclosed
US-8507734-B2 Pharmaceutical compositions comprising monoterpenes NEONC TECHNOLOGIES INC. (US) 2013-08-13 US disclosed
US-8507734-B2 Pharmaceutical compositions comprising monoterpenes NEONC TECHNOLOGIES INC. (US) 2013-08-13 US disclosed
US-20110280860-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES NEONC TECHNOLOGIES INC. 2011-11-17 US disclosed
US-20110280860-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES NEONC TECHNOLOGIES INC. 2011-11-17 US disclosed
US-20110280860-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES NEONC TECHNOLOGIES INC. 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239730-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES SQLE, DHPS, GGPS1 ALOX15 35/4885CYP1B1 26/4885ALDH1A1 793/4885
US-20210130271-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES SQLE, DHPS, GGPS1 ALOX15 35/4885CYP1B1 26/4885ALDH1A1 793/4885
US-20110280860-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES SQLE, DHPS, GGPS1 ALOX15 35/4885CYP1B1 26/4885ALDH1A1 793/4885
US-10899691-B2 Pharmaceutical compositions comprising monoterpenes SQLE, DHPS, GGPS1 ALOX15 35/4885CYP1B1 26/4885ALDH1A1 793/4885
US-20230405125-A1 TREATMENT OF RECURRENT GIOBLASTOMA WITH PERILLYL ALCOHOL IDH3A, IDH1, IDH3B ALOX15 1329/4885CYP1B1 2195/4885ALDH1A1 162/4885
US-20130303807-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES SQLE, DHPS, GGPS1 ALOX15 35/4885CYP1B1 26/4885ALDH1A1 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.