Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.60 |
| ▸ | PNLIP | P16233 | 3/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783970 | 0.89 | EPHX2 (0.60) | EPHX2PNLIPEPHX1MEN1KMT2A | |
| SCHEMBL4686717 | 0.89 | EPHX2 (0.60) | EPHX2PNLIPEPHX1MEN1KMT2A | |
| SCHEMBL4787221 | 0.87 | EPHX1 (0.52) | EPHX2PNLIPEPHX1KMT2AALDH1A1 | |
| SCHEMBL4787374 | 0.87 | KDR (0.54) | EPHX2EPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL6566860 | 0.83 | EPHX2 (0.69) | EPHX2EPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL4787430 | 0.83 | EPHX2 (0.54) | EPHX2PNLIPEPHX1MEN1KMT2A | |
| SCHEMBL4688997 | 0.81 | EPHX2 (0.55) | EPHX2PNLIPEPHX1MEN1KMT2A | |
| SCHEMBL4238208 | 0.80 | PKM (0.53) | PNLIPHTT | |
| SCHEMBL4787261 | 0.78 | KDR (0.52) | EPHX2PNLIPEPHX1MEN1KMT2A | |
| SCHEMBL11832585 | 0.78 | MEN1 (0.68) | MEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |