Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683265 | 0.89 | EPHX1 (0.46) | EPHX2KMT2AEPHX1NPC1RAB9A | |
| SCHEMBL4787430 | 0.87 | EPHX2 (0.54) | EPHX2MEN1KMT2APNLIPEPHX1 | |
| SCHEMBL4688990 | 0.83 | PKM (0.50) | MEN1KMT2APNLIPNPC1RAB9A | |
| SCHEMBL4783970 | 0.81 | EPHX2 (0.60) | EPHX2MEN1KMT2APNLIPEPHX1 | |
| SCHEMBL4785405 | 0.81 | EPHX2 (0.60) | EPHX2MEN1KMT2APNLIPEPHX1 | |
| SCHEMBL4686717 | 0.81 | EPHX2 (0.60) | EPHX2MEN1KMT2APNLIPEPHX1 | |
| SCHEMBL4686797 | 0.79 | CCR3 (0.50) | EPHX2MEN1KMT2APNLIPALDH1A1 | |
| SCHEMBL4686866 | 0.79 | CCR3 (0.44) | EPHX2MEN1KMT2APNLIP | |
| SCHEMBL4783512 | 0.78 | EPHX2 (0.49) | EPHX2MEN1KMT2ARAB9ATBXA2R | |
| SCHEMBL6566860 | 0.77 | EPHX2 (0.69) | EPHX2MEN1KMT2AEPHX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |