Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14338677 | 0.87 | EPHX1 (0.62) | EPHX2POLBEPHX1HTTALDH1A1 | |
| SCHEMBL6566759 | 0.86 | EPHX1 (0.57) | EPHX2EPHX1HTTALDH1A1 | |
| SCHEMBL8598636 | 0.85 | EPHX1 (0.60) | EPHX2EPHX1HTTALDH1A1 | |
| SCHEMBL8603136 | 0.85 | EPHX1 (0.60) | EPHX2EPHX1HTTALDH1A1 | |
| SCHEMBL320808 | 0.84 | ALDH1A1 (0.61) | POLBHTTALDH1A1MEN1KMT2A | |
| SCHEMBL8777974 | 0.84 | EPHX2 (0.80) | EPHX2EPHX1HTTALDH1A1MEN1 | |
| SCHEMBL12989362 | 0.84 | QPCT (0.63) | POLBEPHX1HTTMEN1KMT2A | |
| Bromide SCHEMBL320987 | 0.83 | ALDH1A1 (0.60) | POLBHTTALDH1A1MEN1KMT2A | |
| SCHEMBL5183161 | 0.83 | CNR1 (0.58) | EPHX2EPHX1HTTALDH1A1 | |
| SCHEMBL4348602 | 0.83 | EPHX2 (0.74) | EPHX2EPHX1HTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |