Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785572 | 0.85 | EPHX1 (0.51) | KDRMTNR1BEPHX1ALDH1A1HTT | |
| SCHEMBL4786463 | 0.83 | KDR (0.56) | KDRMTNR1BEPHX1ALDH1A1HTT | |
| SCHEMBL4787089 | 0.83 | EPHX1 (0.61) | KDREPHX1ALDH1A1HTTHDAC1 | |
| SCHEMBL4788031 | 0.83 | KDR (0.52) | KDRMTNR1BEPHX1ALDH1A1HTT | |
| SCHEMBL4689064 | 0.83 | KMT2A (0.58) | KDRMTNR1BEPHX1ALDH1A1HTT | |
| SCHEMBL12362189 | 0.82 | EPHX1 (0.65) | KDRMTNR1BEPHX1ALDH1A1HTT | |
| SCHEMBL4786912 | 0.81 | KDR (0.54) | KDREPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL4786099 | 0.81 | EPHX1 (0.52) | KDREPHX1ALDH1A1HTTHDAC1 | |
| SCHEMBL4236682 | 0.80 | PKM (0.64) | MTNR1BALDH1A1HDAC1MTNR1APKM | |
| SCHEMBL4683734 | 0.79 | KDR (0.56) | KDREPHX1ALDH1A1HTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |