Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | ALDH2 | P05091 | 7/20 | 0.65 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784867 | 0.90 | PARK7 (0.82) | PARK7ALDH1A1ALDH2ALDH3A1CASP3 | |
| SCHEMBL4784991 | 0.89 | PARK7 (0.81) | PARK7ALDH1A1ALDH2ALDH3A1CASP3 | |
| SCHEMBL4736331 | 0.86 | PARK7 (0.75) | PARK7ALDH1A1ALDH2ALDH3A1CASP3 | |
| SCHEMBL4785342 | 0.84 | PARK7 (0.72) | PARK7ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL4786048 | 0.83 | PARK7 (0.78) | PARK7ALDH1A1ALDH2ALDH3A1CASP3 | |
| SCHEMBL16799029 | 0.79 | ALDH1A1 (1.00) | PARK7ALDH1A1ALDH2ALDH3A1CASP3 | |
| SCHEMBL4734658 | 0.78 | PARK7 (0.72) | PARK7ALDH1A1ALDH2ALDH3A1MGLL | |
| SCHEMBL4785634 | 0.76 | PARK7 (0.61) | PARK7ALDH1A1ALDH2ALDH3A1CA12 | |
| SCHEMBL18954806 | 0.76 | PARK7 (0.60) | PARK7ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL30774299 | 0.75 | PARK7 (0.82) | PARK7ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |