Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737404 | 0.89 | PARK7 (0.76) | PARK7ALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL4786048 | 0.88 | PARK7 (0.78) | PARK7ALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL4784991 | 0.87 | PARK7 (0.81) | PARK7ALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL4785743 | 0.84 | PARK7 (1.00) | PARK7ALDH1A1ALDH3A1ALDH2 | |
| SCHEMBL4784867 | 0.80 | PARK7 (0.82) | PARK7ALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL4784997 | 0.79 | PARK7 (0.57) | PARK7ALDH1A1 | |
| SCHEMBL4735921 | 0.78 | PARK7 (1.00) | PARK7ALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL6965415 | 0.74 | NR1H2 (0.67) | PARK7ALDH1A1SIGMAR1NR1H2NR1H3 | |
| SCHEMBL4736331 | 0.73 | PARK7 (0.75) | PARK7ALDH1A1ALDH3A1ALDH2CHRM5 | |
| SCHEMBL12431372 | 0.73 | HEXA (0.60) | PARK7ALDH1A1SIGMAR1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |