Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943368 | 0.95 | MEN1 (0.38) | MEN1KMT2AALDH1A1TSHRPDE7A | |
| SCHEMBL2884469 | 0.86 | TSHR (0.32) | MEN1KMT2ATSHRTP53MAPT | |
| SCHEMBL2884549 | 0.75 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1TSHRPDE7A | |
| SCHEMBL22325936 | 0.74 | EPAS1 (0.43) | MEN1KMT2AALDH1A1PDE7AEPAS1 | |
| SCHEMBL22326107 | 0.73 | PDE7A (0.39) | MEN1KMT2AALDH1A1PDE7ALMNA | |
| SCHEMBL2881452 | 0.73 | MAPT (0.52) | MEN1KMT2AALDH1A1TSHREPAS1 | |
| SCHEMBL22325952 | 0.71 | EPAS1 (0.46) | MEN1KMT2AALDH1A1PDE7AEPAS1 | |
| SCHEMBL4556511 | 0.70 | MAPT (0.49) | MEN1KMT2AALDH1A1TSHREPAS1 | |
| Iodide SCHEMBL4440818 | 0.70 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1TSHRPDE7A | |
| SCHEMBL22326087 | 0.70 | PDE7A (0.42) | MEN1KMT2AALDH1A1PDE7ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076223-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2008-06-26 | — | — | WO | disclosed |