Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.67 |
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | CLK1 | P49759 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785744 | 0.86 | ALDH1A1 (0.58) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4746882 | 0.85 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4750765 | 0.84 | KMT2A (0.56) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL4750943 | 0.84 | MAPK1 (0.63) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL4746954 | 0.83 | ABL1 (0.52) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4789362 | 0.83 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4789366 | 0.83 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4789364 | 0.83 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4747401 | 0.82 | MAPT (0.67) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4746879 | 0.82 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |