Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14103924 | 0.87 | PDE4B (0.72) | PDE4BABCB1PDE4D | |
| SCHEMBL4785416 | 0.76 | KMT2A (0.59) | PDE4BABCB1 | |
| SCHEMBL20149733 | 0.75 | PDE4B (0.65) | PDE4BPDE4D | |
| SCHEMBL28985612 | 0.73 | ABCB1 (0.76) | ABCB1 | |
| SCHEMBL4785886 | 0.72 | HPGD (0.57) | — | |
| SCHEMBL4787185 | 0.71 | KMO (0.50) | PDE4B | |
| SCHEMBL4783781 | 0.71 | CNR1 (0.60) | — | |
| SCHEMBL31563594 | 0.71 | ABCB1 (0.80) | ABCB1 | |
| SCHEMBL8817555 | 0.70 | CA1 (0.54) | — | |
| SCHEMBL4739367 | 0.70 | CA1 (0.62) | PDE4BABCB1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008095852-A1 | BRONCHORELAXING ARYLAMIDES | RESPIRATORIUS AB (SE) | 2008-08-14 | — | — | WO | disclosed |