Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL7004500 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL2974121 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL906010 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL1940651 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL1135949 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL5311584 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL6690080 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL9405454 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL372318 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL9364269 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 71861 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144725-A1 | TOOTH DESENSITIZING ORAL CARE COMPOSITIONS, DEVICES, AND METHODS | THE PROCTER & GAMBLE COMPANY (US) | 2026-05-28 | — | — | US | claimed |
| EP-4746864-A1 | C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION | Keto Innovations, LLC (US) | 2026-05-27 | — | — | EP | claimed |
| EP-3836899-B1 | CHEMOTHERAPEUTIC PHARMACEUTICAL SUSPENSION FOR ORAL DOSAGE | ONCOSOL LTD (GB) | 2026-05-27 | — | — | EP | claimed |
| EP-4401569-B1 | BULK MELT-TO-MAKE PECTIN-BASED GUMMY MIX PRECURSOR AND METHODS OF MAKING AND USING | M2M GUMMIES LLC (US) | 2026-05-27 | — | — | EP | claimed |
| CN-121369665-B | Delicious peptide-based low-salt thick broad-bean sauce and production process thereof | Sichuan Dandan Pixian Bean Paste Group Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116553684-B | Device and method for electrochemical oxidation total denitrification of ammonia nitrogen wastewater | EAST CHINA JIAOTONG UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122074633-A | Flavour composition, aqueous food composition containing said flavour composition, preparation and use thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074562-A | Jam inner core for cheese food and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121873800-B | Alkali polishing additive, polishing solution and polishing method | Jiageng Innovation Laboratory (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122094704-A | Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material | — | 2026-05-26 | — | — | CN | claimed |
| US-3994729-A | DIALDEHYDES, FIXING WITH THIOSULFATES, ALUMINUM SALT, TARTARIC ACID OR CITRIC ACID | FUJI PHOTO FILM CO., LTD. (JA) | 1976-11-30 | — | — | US | claimed |
| US-3983252-A | Stable dialdehyde-containing disinfectant compositions and methods | BUCHALTER GILBERT | 1976-09-28 | — | — | US | claimed |
| US-3982025-A | Soy cheese spread and process for preparing same | FUJI OIL COMPANY, LTD. (JA) | 1976-09-21 | — | — | US | claimed |
| US-3973074-A | POTASSIUM HYDROXIDE OR CARBONATE | MACMILLAN BLOEDEL LIMITED (CA) | 1976-08-03 | — | — | US | claimed |
| US-3968263-A | CALCIUM PHOSPHATE | GENERAL FOODS CORPORATION (US) | 1976-07-06 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |
| US-3962482-A | Clear, elastic, water gels based on carrageenan | UNIROYAL, LTD. (CA) | 1976-06-08 | — | — | US | claimed |
| US-3941723-A | Crystallized alkali metal silicate with sequestering agents | PHILADELPHIA QUARTZ COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-3935323-A | CHEESE WHEY | STAUFFER CHEMICAL COMPANY (US) | 1976-01-27 | — | — | US | claimed |
| US-3932655-A | CHELATING AGENTS, N-ALKYL BENZALKONIUM CHLORIDES | INTERNATIONAL PHARMAKON LABORATORIES, INC. (US) | 1976-01-13 | — | — | US | claimed |