Citric Acid

Citric Acid

SCHEMBL7004500

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nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BHRH2IMPA1

The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA4 P22748 4/20 0.89
ALDH1A1 P00352 1/20 0.33
CASP1 P29466 1/20 0.32
FAHD1 Q6P587 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL2974121 1.00 CA4 (0.89) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL906010 1.00 CA4 (0.89) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL47867 1.00 CA4 (0.89) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL1940651 0.97 CA4 (0.84) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL1135949 0.97 CA4 (0.84) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL5311584 0.97 CA4 (0.84) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL6690080 0.97 CA4 (0.94) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL9405454 0.97 CA4 (0.84) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL372318 0.97 CA4 (0.84) CA4ALDH1A1CASP1FAHD1
Citric Acid SCHEMBL9364269 0.97 CA4 (0.84) CA4ALDH1A1CASP1FAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012119811-A2 COMPOSITION UNILEVER PLC (GB) 2012-09-13 WO disclosed
EP-1341502-A2 HAIR CONDITIONING COMPOSITIONS AND THEIR USE IN HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-09-10 EP disclosed
EP-0876134-B1 HAIR COLORING COMPOSITIONS PROCTER & GAMBLE (US) 2003-09-03 EP disclosed
WO-2003068177-A2 TWO STEP PERMANENT COLOURING OF HAIR UNILEVER PLC (GB) 2003-08-21 WO disclosed
EP-1267809-A1 HAIR COLOURING AND CONDITIONING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-01-02 EP disclosed
EP-1267810-A2 METHOD FOR COLOURING HAIR THE PROCTER & GAMBLE COMPANY (US) 2003-01-02 EP disclosed
EP-1251821-A1 HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-10-30 EP disclosed
EP-1221932-A1 HAIR COLORING COMPOSITIONS AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2002-07-17 EP disclosed
WO-2002047632-A2 HAIR CONDITIONING COMPOSITIONS COMPRISING AMINOFUNCTIONA POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 2002-06-20 WO disclosed
EP-0966249-A4 HAIR COLORING COMPOSITIONS PROCTER & GAMBLE (US) 2001-12-19 EP disclosed
WO-1998027943-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027942-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027941-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027945-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1997024106-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024108-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024107-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
US-4867942-A Process for the preparation of an effervescent granular material, effervescent granular material prepared by this process, as well as the use thereof GERGELY GERHARD (AT) 1989-09-19 US disclosed
US-4649171-A METAL CITRATE; CORROSION RESISTANCE HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-10 US disclosed