Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL7004500 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL2974121 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL47867 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL1940651 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL1135949 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL5311584 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL6690080 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL9405454 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL372318 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL9364269 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9113647-B2 | Flavored and edible colored waxes and methods for precision deposition on edible substrates | SENSIENT COLORS LLC (US) | 2015-08-25 | — | — | US | claimed |
| US-20140144454-A1 | COMPOSITION FOR COATING A PAPER WRAPPER FOR SMOKING ARTICLES | MIQUEL Y COSTAS & MIQUEL, S.A. (ES) | 2014-05-29 | — | — | US | claimed |
| EP-2719293-A1 | COMPOSITION FOR COATING A PAPER WRAPPER FOR SMOKING REQUISITES | Miquel y Costas & Miquel, S.A. (ES) | 2014-04-16 | — | — | EP | claimed |
| EP-2277957-A1 | Ink-jettable flavored fluids for printing on edible substrates | SENSIENT IMAGING TECHNOLOGIES INC. (US) | 2011-01-26 | — | — | EP | claimed |
| EP-1902107-A1 | INK-JETTABLE FLAVORED FLUIDS FOR PRINTING ON EDIBLE SUBSTRATES | SENSIENT IMAGING TECHNOLOGIES INC. (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007005063-A1 | INK-JETTABLE FLAVORED FLUIDS FOR PRINTING ON EDIBLE SUBSTRATES | SENSIENT IMAGING TECHNOLOGIES INC. (US) | 2007-01-11 | — | — | WO | claimed |
| US-5157030-A | Adding lecithin polysorbate, glycerol monostearate, or polyether surfactant | SOLUPRIN PHARMACEUTICALS, INC. | 1992-10-20 | — | — | US | claimed |
| JP-2200495-A | — | — | None | — | — | JP | disclosed |
| CN-113973845-B | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-113973845-A | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-9113647-B2 | Flavored and edible colored waxes and methods for precision deposition on edible substrates | SENSIENT COLORS LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-20140144454-A1 | COMPOSITION FOR COATING A PAPER WRAPPER FOR SMOKING ARTICLES | MIQUEL Y COSTAS & MIQUEL, S.A. (ES) | 2014-05-29 | — | — | US | disclosed |
| EP-2719293-A1 | COMPOSITION FOR COATING A PAPER WRAPPER FOR SMOKING REQUISITES | Miquel y Costas & Miquel, S.A. (ES) | 2014-04-16 | — | — | EP | disclosed |
| WO-2008003069-A2 | FLAVORED AND EDIBLE COLORED FLUIDS FOR PRINTING ON EDIBLE SUBSTRATE | SENSIENT COLORS INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| WO-2007005063-A1 | INK-JETTABLE FLAVORED FLUIDS FOR PRINTING ON EDIBLE SUBSTRATES | SENSIENT IMAGING TECHNOLOGIES INC. (US) | 2007-01-11 | — | — | WO | disclosed |
| EP-0777422-B1 | PROCESS FOR PRODUCING A GEL-FORMING SUBSTANCE | PFEIFER & LANGEN (DE) | 2001-01-03 | — | — | EP | disclosed |
| EP-0777422-A1 | PROCESS FOR PRODUCING A GEL-FORMING SUBSTANCE | GOEMAR S.A. (FR) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996002150-A1 | PROCESS FOR PRODUCING A GEL-FORMING SUBSTANCE | PFEIFER & LANGEN (DE) | 1996-02-01 | — | — | WO | disclosed |
| JP-H02200495-A | METHOD FOR PROCESSING RADIATION SENSITIVE MEMBER | E I DU PONT DE NEMOURS & CO | 1990-08-08 | — | — | JP | disclosed |
| US-4867942-A | Process for the preparation of an effervescent granular material, effervescent granular material prepared by this process, as well as the use thereof | GERGELY GERHARD (AT) | 1989-09-19 | — | — | US | disclosed |