Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | LMNA | P02545 | 11/20 | 0.72 |
| ▸ | MAPT | P10636 | 10/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.63 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.63 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749664 | 0.79 | LMNA (0.67) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL17073218 | 0.78 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL31162680 | 0.77 | LMNA (0.90) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL3607443 | 0.75 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL532616 | 0.74 | GAA (0.64) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL532240 | 0.72 | GAA (0.65) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL24090298 | 0.72 | NFKB1 (0.72) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL22076816 | 0.72 | NPC1 (1.00) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL24090252 | 0.72 | NFKB1 (1.00) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL17073122 | 0.71 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |