Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752089 | 0.70 | EGFR (0.53) | CSF1RKDM4EGRM4LMNAHDAC6 | |
| SCHEMBL16207823 | 0.69 | CES2 (0.44) | CSF1RSYKLMNAMAPT | |
| SCHEMBL4748557 | 0.69 | MAP2K1 (0.48) | CSF1RGRM4MCHR1 | |
| SCHEMBL14620842 | 0.67 | GRIN1 (0.47) | KDM4EGRM4HDAC6MEN1KMT2A | |
| SCHEMBL4790727 | 0.67 | ALDH1A1 (0.43) | CSF1RSYKKDM4EKMT2A | |
| SCHEMBL27413036 | 0.66 | GRM4 (0.59) | KDM4EGRM4HDAC6MEN1NPC1 | |
| SCHEMBL20714669 | 0.66 | MAPT (0.43) | KDM4EGRM4HDAC6MEN1KMT2A | |
| SCHEMBL31051269 | 0.65 | MAPT (0.41) | KDM4EGRM4LMNAMEN1RAB9A | |
| SCHEMBL27398849 | 0.65 | MAPT (0.41) | KDM4EGRM4LMNAMEN1RAB9A | |
| SCHEMBL3347725 | 0.64 | NPC1 (0.47) | CSF1RKDM4ELMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132464-A2 | MEK5 AND RELATED PROTEINS AS BIOMARKERS OF NEURODEGENERATIVE DISEASES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2008-11-06 | — | — | WO | disclosed |