SCHEMBL4786882

SCHEMBL4786882

NCCC(N)CCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 6/20 0.64
ANPEP P15144 3/20 0.64
GABRP O00591 3/20 0.52
GABRD O14764 3/20 0.52
GABRA1 P14867 3/20 0.52
GABRB1 P18505 3/20 0.52
GABRG2 P18507 3/20 0.52
GABRB3 P28472 3/20 0.52
GABRA5 P31644 3/20 0.52
GABRA3 P34903 3/20 0.52
GABRA2 P47869 3/20 0.52
GABRB2 P47870 3/20 0.52
GABRA4 P48169 3/20 0.52
GABRE P78334 3/20 0.52
GABRA6 Q16445 3/20 0.52
GABRG1 Q8N1C3 3/20 0.52
GABRG3 Q99928 3/20 0.52
GABRQ Q9UN88 3/20 0.52
CYP1A2 P05177 2/20 0.52
GRM8 O00222 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289090 0.89 ENPEP (0.76) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL27999729 0.86 ENPEP (0.59) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL289292 0.86 ENPEP (0.59) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL288592 0.85 ENPEP (0.64) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL28208979 0.85 ENPEP (0.64) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL289205 0.84 ENPEP (0.57) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL661389 0.84 ENPEP (0.57) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL14713708 0.84 ALDH1A1 (0.66) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL288818 0.82 ALDH1A1 (0.58) ENPEPANPEPGABRPGABRDGABRA1
SCHEMBL27999714 0.82 ALDH1A1 (0.58) ENPEPANPEPGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4324882-A2 BINDERS Knauf Insulation SPRL (BE) 2024-02-21 EP disclosed
EP-3146010-B1 BINDERS KNAUF INSULATION INC (US) 2023-12-13 EP disclosed
US-11332577-B2 Binders KNAUF INSULATION SPRL (BE) 2022-05-17 US disclosed
US-20190119446-A1 BINDERS KNAUF INSULATION, INC. 2019-04-25 US disclosed
US-20170174836-A1 BINDERS KNAUF INSULATION SPRL (BE) 2017-06-22 US disclosed
WO-2008077194-A1 RECEPTOR AGONISTS XENOME LTD (AU) 2008-07-03 WO disclosed