Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336856 | 0.91 | ALDH1A1 (0.76) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL9618680 | 0.89 | LMNA (0.71) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| Adipic Acid SCHEMBL28232315 | 0.89 | ALDH1A1 (0.74) | ALDH1A1ENPEPKMT2AMEN1ALOX15 | |
| SCHEMBL27705304 | 0.89 | ALDH1A1 (0.80) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL29255900 | 0.89 | ALDH1A1 (0.80) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL11545521 | 0.89 | ALDH1A1 (0.73) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL27762577 | 0.89 | ALDH1A1 (0.80) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL16319841 | 0.86 | ALDH1A1 (0.70) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL28419762 | 0.85 | LMNA (0.64) | ALDH1A1ENPEPNFKB1CYP2D6LMNA | |
| SCHEMBL8637959 | 0.84 | ENPEP (0.67) | ALDH1A1ENPEPNFKB1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8512755-B2 | Compact multifunctional ligand to enhance colloidal stability of nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-08-20 | — | — | US | disclosed |
| US-20130045499-A1 | Compact Multifunctional Ligand to Enhance Colloidal Stability of Nanoparticles | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045499-A1 | Compact Multifunctional Ligand to Enhance Colloidal Stability of Nanoparticles | EPCAM, SLC7A1, CAD | ALDH1A1 2504/4885ENPEP 2331/4885NFKB1 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.