SCHEMBL4786965

SCHEMBL4786965

Fc1cccc(-c2nc(Cl)nc(Cl)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
IDO1 P14902 2/20 0.44
DPP4 P27487 2/20 0.44
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
TP53 P04637 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ESR2 Q92731 1/20 0.42
NOTUM Q6P988 1/20 0.41
HPGDS O60760 1/20 0.41
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30414816 1.00 NT5E (0.46) NT5EMEN1KMT2AALDH1A1HPGD
SCHEMBL24961152 0.91 MEN1 (0.50) NT5EMEN1KMT2AALDH1A1HPGD
SCHEMBL27795616 0.88 RAB9A (0.49) NT5EMEN1KMT2ADPP4KDM4E
SCHEMBL27095783 0.85 TAAR1 (0.56) MEN1KMT2AIDO1DPP4KDM4E
SCHEMBL11293557 0.84 LMNA (0.47) NT5EMEN1KMT2AIDO1DPP4
SCHEMBL25672123 0.84 TAAR1 (0.53) NT5EMEN1KMT2AALDH1A1HPGD
SCHEMBL375243 0.82 LMNA (0.46) NT5EMEN1KMT2AALDH1A1IDO1
SCHEMBL29560753 0.80 IDH1 (0.49) ALDH1A1HPGDL3MBTL1KDM4EPDGFRB
SCHEMBL15102654 0.80 IDH1 (0.49) ALDH1A1HPGDL3MBTL1KDM4EPDGFRB
SCHEMBL12958862 0.79 LMNA (0.43) NT5EMEN1KMT2AIDO1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549059-B Organic compound, and electronic device and electronic apparatus including the same 陕西莱特光电材料股份有限公司 2023-04-28 CN disclosed
CN-113549059-A Organic compound, and electronic device and electronic apparatus comprising same 陕西莱特光电材料股份有限公司 2021-10-26 CN disclosed
WO-2008072850-A1 TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE AMOREPACIFIC CORPORATION (KR) 2008-06-19 WO disclosed
WO-2008072850-A1 TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE AMOREPACIFIC CORPORATION (KR) 2008-06-19 WO disclosed