Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12958862 | 0.85 | LMNA (0.43) | LMNANT5EIDO1DPP4MEN1 | |
| SCHEMBL27095783 | 0.83 | TAAR1 (0.56) | IDO1DPP4MEN1KMT2AKDM4E | |
| SCHEMBL11293557 | 0.82 | LMNA (0.47) | LMNANT5EIDO1DPP4MEN1 | |
| SCHEMBL30414816 | 0.82 | NT5E (0.46) | NT5EIDO1DPP4MEN1KMT2A | |
| SCHEMBL4786965 | 0.82 | NT5E (0.46) | NT5EIDO1DPP4MEN1KMT2A | |
| SCHEMBL1809226 | 0.81 | PDGFRB (0.48) | NT5EMEN1KMT2AALDH1A1PDGFRB | |
| SCHEMBL12958861 | 0.79 | DPP4 (0.48) | DPP4MEN1KMT2AKDM4EMAPT | |
| SCHEMBL12958859 | 0.79 | TRPM8 (0.42) | LMNANT5EMEN1KMT2AKDM4E | |
| SCHEMBL1810399 | 0.79 | DPP4 (0.48) | NT5EDPP4MEN1KMT2AKDM4E | |
| SCHEMBL24961152 | 0.78 | MEN1 (0.50) | LMNANT5EDPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309557-B2 | Pyrimidin-4-ylpropanedinitrile derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-11-13 | — | — | US | disclosed |
| CN-101646657-B | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL CO JP | 2012-08-08 | — | — | CN | disclosed |
| US-8158787-B2 | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2408305-A1 | PYRIMINDINE-4-YLPROPANE DINITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108611-A1 | PYRIMINDINE-4-YLPROPANE DINITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2010-09-30 | — | — | WO | disclosed |
| US-20100240536-A1 | PYRIMIDIN-4-YLPROPANEDINITRILE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| EP-2229813-A1 | Pyrimidine-4-ylpropandinitrile derivatives, method for their manufacture and their use as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-20100160630-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2128141-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160630-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | DPYD, TYMP, TST | LMNA 4884/4885NT5E 3328/4885IDO1 3575/4885 |
| US-20100240536-A1 | PYRIMIDIN-4-YLPROPANEDINITRILE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | DDT, PLPBP, HPD | LMNA 3510/4885NT5E 2471/4885IDO1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.