Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | HTR1A | P08908 | 2/20 | 0.78 |
| ▸ | HTR1D | P28221 | 2/20 | 0.78 |
| ▸ | HTR1B | P28222 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787341 | 1.00 | KDM4E (0.78) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4784837 | 0.88 | HTR1D (1.00) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL30058389 | 0.88 | HTR1D (1.00) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4784832 | 0.88 | HTR1D (1.00) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4787880 | 0.87 | HTR1D (0.79) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4787875 | 0.87 | HTR1D (0.79) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4788261 | 0.85 | HTR1D (0.79) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4788256 | 0.85 | HTR1D (0.79) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL18622645 | 0.84 | HTR1A (0.81) | KDM4EALDH1A1LMNACYP1A2HTR1A | |
| SCHEMBL4784970 | 0.84 | HTR1A (0.80) | KDM4EALDH1A1LMNACYP1A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118445-A9 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORP (US) | 2008-12-04 | — | — | WO | claimed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | claimed |
| WO-2008118445-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008118445-A9 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORP (US) | 2008-12-04 | — | — | WO | disclosed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | disclosed |
| WO-2008118445-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | GLO1, ESD, GLB1 | KDM4E 1027/4885ALDH1A1 349/4885LMNA 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.