Methane

Methane

SCHEMBL4787385

C.CCCCCCCCCCCCCCCCC1(C)CCC[Si](C)(C)O1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28408061 0.98 SIRT2 (0.32) SIRT2
SCHEMBL3058860 0.98 SIRT2 (0.32) SIRT2
SCHEMBL8813475 0.98 SIRT2 (0.32) SIRT2
SCHEMBL29024225 0.98 SIRT2 (0.32) SIRT2
SCHEMBL408490 0.98 SIRT2 (0.32) SIRT2
SCHEMBL3248123 0.98 SIRT2 (0.32) SIRT2
SCHEMBL28994499 0.98 SIRT2 (0.32) SIRT2
SCHEMBL28391020 0.97 SIRT2 (0.31) SIRT2
SCHEMBL28133293 0.91
SCHEMBL6679396 0.83 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008090489-A2 COSMETIC SKINCARE USE OF IRON GLUCONATE COMBINATIONS L'OREAL (FR) 2008-07-31 WO disclosed
US-20080008670-A1 Process for colouring dark skin L'OREAL (FR) 2008-01-10 US disclosed
US-20070081954-A1 Dispersion of polymer particles, composition comprising it and cosmetic treatment method L'OREAL S.A. (FR) 2007-04-12 US disclosed
EP-1133979-B1 Use of specific fatty compounds for modifying the physico-chemical properties of the skin and/or the mucous membrane as agents for preventing or reducing the adhesion of micro-organisms thereon OREAL (FR) 2005-10-26 EP disclosed
EP-1133979-A2 Use of specific fatty compounds for modifying the physico-chemical properties of the skin and/or the mucous membrane as agents for preventing or reducing the adhesion of micro-organisms thereon L'OREAL (FR) 2001-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080008670-A1 Process for colouring dark skin CUTA, DSG1, TYR SIRT2 4719/4885
US-20070081954-A1 Dispersion of polymer particles, composition comprising it and cosmetic treatment method KRT18, KRTCAP2, KIF18B SIRT2 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.