SCHEMBL4787434

SCHEMBL4787434

NC(=O)C(=O)C(NCC(=O)O)C(=O)C(N)=O

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
PTGS2 P35354 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LDHA P00338 2/20 0.30
LDHB P07195 1/20 0.30
SRR Q9GZT4 1/20 0.30
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28313334 0.76 ALDH1A1 (0.31) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL3179343 0.74 LDHA (0.37) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL7783653 0.69
SCHEMBL28536446 0.68 LDHA (0.41) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL9052983 0.67 ALDH1A1 (0.31) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL7763267 0.67 CTH (0.38) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL2560090 0.67 ALDH1A1 (0.40) ALDH1A1LMNAMAPTPTGS2TDP1
SCHEMBL987124 0.66
SCHEMBL7432682 0.65 CA14 (0.45) ALDH1A1LMNAMAPTPTGS2TDP1
Hydrochloric Acid SCHEMBL7319087 0.65 ALDH1A1 (0.39) ALDH1A1LMNAMAPTPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008135639-A2 NOVEL USEFUL INHIBITORS JAAKKOLA PANU (FI) 2008-11-13 WO disclosed